- Metronidazole 2 g taken as a single oral dose with food
or
- Tinidazole 2 g taken as a single oral dose with food
Avoid alcohol during and for 48 hours after imidazole containing treatment regimens
Persistence following stat treatment:
- Exclude non-compliance
- Ensure concomitant partner treatment
- Metronidazole 400 mg bd for 7 days or
- Metronidazole 2 g daily for 5 days or
- Tinidazole 2g daily for 5 days
If persistence remains, consult with a sexual health physician
Pregnancy:
- Symptomatic trichomoniasis:
Manage as for nonpregnant woman. Metronidazole (category B) can be used in all trimesters Clotrimazole 1% vaginal cream can be used to relieve symptoms however there is a low cure rate
- Asymptomatic trichomoniasis:
Currently controversial after a recent publication reported an increased risk of adverse pregnancy outcome in asymptomatic pregnant women with trichomonas treated with metronidazole - consult with senior sexual health physician