The IMPACT study looked at the prevalence of various HPV genotypes in unvaccinated men following a national female HPV vaccination program.
We recruited men aged 16–35 years to participate in the study. Participants provided a self-collected penile swab sample for HPV genotyping. They also completed a demographic and risk factor questionnaire.
We found that the 4 genotypes in the vaccine provided to females were much lower in unvaccinated males aged less than 26 years (3%) than in those aged more than 26 years (14%). The other genotypes not included in the vaccine were similar in men aged less than 26 years and in those aged 26 or more years. Unvaccinated younger men may have benefited from vaccination of their female partners (herd protection).
Publications
Human papillomavirus prevalence in unvaccinated heterosexual men after a national female vaccination program
Dorothy A. Machalek, Eric P. F. Chow, Suzanne M. Garland, Rebecca Wigan, Alyssa M. Cornall, Christopher K. Fairley, John M Kaldor, Jane S. Hocking, Henrietta Williams, Anna McNulty, Charlotte Bell, Lewis Marshall, Catriona Ooi, Marcus Y. Chen, and Sepehr N. Tabrizi
(2017), Journal of Infectious Disease,